1033 TGF-β/Smad pathway is not required for epidermal LC development
نویسندگان
چکیده
منابع مشابه
TGF-β1-Smad signaling pathways are not required for epidermal LC homeostasis
Langerhans cells (LCs) are skin-homing dendritic cells (DCs) that have long been considered to be prototypic sentinel DCs due to their prominent position at the environmental barrier, and are essential for the induction of skin immunity and tolerance [1]. Transforming growth factor-β1 (TGF-β1) is a key factor in epidermal LC development and maintenance. The presence of TGF-β1 is a prerequisite ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2018
ISSN: 0022-202X
DOI: 10.1016/j.jid.2018.03.1045